Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke

Tissue plasminogen activator-induced reperfusion injury after stroke revisited.

Tissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke

Tissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke To the Editor: Jannes et al1 reported that a polymorphism in the tissue plasminogen activator (tPA) gene ( 7351C/T) was associated with ischemic stroke in an Australian population. Stratification for stroke subtype demonstrated an association with lacunar infarction (OR: 2.7; 95% CI, 1.1 to 6.7), but not with other stroke subt...

Tissue plasminogen activator -7351C/T polymorphism and lacunar stroke.

Tissue Plasminogen Activator 7351C/T Polymorphism and Lacunar Stroke To the Editor: Jannes et al1 reported that a polymorphism in the tissue plasminogen activator (tPA) gene ( 7351C/T) was associated with ischemic stroke in an Australian population. Stratification for stroke subtype demonstrated an association with lacunar infarction (OR: 2.7; 95% CI, 1.1 to 6.7), but not with other stroke subt...

The Outcome of Treatment With Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke

Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...

Tissue-plasminogen activator for acute ischaemic stroke.

BACKGROUND Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of intracerebral hemorrhage in early clinical trials. We performed a randomized, double-blind trial of intravenous recombinant tissue plasminogen activator (t-PA) for ischemic stroke after recent pilot studies suggested that t-PA was beneficial when treatment was begun within t...